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Novel protein kinase D inhibitors cause potent arrest in prostate cancer cell growth and motility
BACKGROUND: Protein kinase D (PKD) has been implicated in a wide range of cellular processes and pathological conditions including cancer. However, targeting PKD therapeutically and dissecting PKD-mediated cellular responses remains difficult due to lack of a potent and selective inhibitor. Previous...
Autores principales: | LaValle, Courtney R, Bravo-Altamirano, Karla, Giridhar, Karthik V, Chen, Jun, Sharlow, Elizabeth, Lazo, John S, Wipf, Peter, Wang, Q Jane |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873968/ https://www.ncbi.nlm.nih.gov/pubmed/20444281 http://dx.doi.org/10.1186/1472-6769-10-5 |
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