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Aldehyde Dehydrogenase (ALDH) Activity Does Not Select for Cells with Enhanced Aggressive Properties in Malignant Melanoma

BACKGROUND: Malignant melanoma is an exceptionally aggressive, drug-resistant and heterogeneous cancer. Recently it has been shown that melanoma cells with high clonogenic and tumourigenic abilities are common, but markers distinguishing such cells from cells lacking these abilities have not been id...

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Detalles Bibliográficos
Autores principales: Prasmickaite, Lina, Engesæter, Birgit Ø., Skrbo, Nirma, Hellenes, Tina, Kristian, Alexandr, Oliver, Nina K., Suo, Zhenhe, Mælandsmo, Gunhild M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874003/
https://www.ncbi.nlm.nih.gov/pubmed/20505780
http://dx.doi.org/10.1371/journal.pone.0010731