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Long term treatment with metformin in patients with type 2 diabetes and risk of vitamin B-12 deficiency: randomised placebo controlled trial

Objectives To study the effects of metformin on the incidence of vitamin B-12 deficiency (<150 pmol/l), low concentrations of vitamin B-12 (150-220 pmol/l), and folate and homocysteine concentrations in patients with type 2 diabetes receiving treatment with insulin. Design Multicentre randomised...

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Detalles Bibliográficos
Autores principales:	de Jager, Jolien, Kooy, Adriaan, Lehert, Philippe, Wulffelé, Michiel G, van der Kolk, Jan, Bets, Daniël, Verburg, Joop, Donker, Ab J M, Stehouwer, Coen D A
Formato:	Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group Ltd. 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874129/ https://www.ncbi.nlm.nih.gov/pubmed/20488910 http://dx.doi.org/10.1136/bmj.c2181

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