Aging, Proteotoxicity, Mitochondria, Glycation, NAD(+) and Carnosine: Possible Inter-Relationships and Resolution of the Oxygen Paradox

It is suggested that NAD(+) availability strongly affects cellular aging and organism lifespan: low NAD(+) availability increases intracellular levels of glycolytic triose phosphates (glyceraldehyde-3-phosphate and dihydroxyacetone-phosphate) which, if not further metabolized, decompose spontaneousl...

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Detalles Bibliográficos
Autor principal: Hipkiss, Alan R.
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2010
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874395/
https://www.ncbi.nlm.nih.gov/pubmed/20552048
http://dx.doi.org/10.3389/fnagi.2010.00010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874395/
https://www.ncbi.nlm.nih.gov/pubmed/20552048
http://dx.doi.org/10.3389/fnagi.2010.00010

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