Cargando…
Aging, Proteotoxicity, Mitochondria, Glycation, NAD(+) and Carnosine: Possible Inter-Relationships and Resolution of the Oxygen Paradox
It is suggested that NAD(+) availability strongly affects cellular aging and organism lifespan: low NAD(+) availability increases intracellular levels of glycolytic triose phosphates (glyceraldehyde-3-phosphate and dihydroxyacetone-phosphate) which, if not further metabolized, decompose spontaneousl...
| Autor principal: | |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Research Foundation
2010
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874395/ https://www.ncbi.nlm.nih.gov/pubmed/20552048 http://dx.doi.org/10.3389/fnagi.2010.00010 |