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Microtubule Depolymerization Potentiates Alpha-Synuclein Oligomerization

Parkinson's disease (PD) is associated with perturbed mitochondria function and alpha-synuclein fibrillization. We evaluated potential mechanistic links between mitochondrial dysfunction and alpha-synuclein aggregation. We studied a PD cytoplasmic hybrid (cybrid) cell line in which platelet mit...

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Detalles Bibliográficos
Autores principales:	Esteves, A. Raquel, Arduíno, Daniela M., Swerdlow, Russell H., Oliveira, Catarina R., Cardoso, Sandra M.
Formato:	Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2010
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874407/ https://www.ncbi.nlm.nih.gov/pubmed/20552056 http://dx.doi.org/10.3389/neuro.24.005.2009

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