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Molecular recognition of organic ammonium ions in solution using synthetic receptors

Ammonium ions are ubiquitous in chemistry and molecular biology. Considerable efforts have been undertaken to develop synthetic receptors for their selective molecular recognition. The type of host compounds for organic ammonium ion binding span a wide range from crown ethers to calixarenes to metal...

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Detalles Bibliográficos
Autores principales: Späth, Andreas, König, Burkhard
Formato: Texto
Lenguaje:English
Publicado: Beilstein-Institut 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874414/
https://www.ncbi.nlm.nih.gov/pubmed/20502608
http://dx.doi.org/10.3762/bjoc.6.32
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author Späth, Andreas
König, Burkhard
author_facet Späth, Andreas
König, Burkhard
author_sort Späth, Andreas
collection PubMed
description Ammonium ions are ubiquitous in chemistry and molecular biology. Considerable efforts have been undertaken to develop synthetic receptors for their selective molecular recognition. The type of host compounds for organic ammonium ion binding span a wide range from crown ethers to calixarenes to metal complexes. Typical intermolecular interactions are hydrogen bonds, electrostatic and cation–π interactions, hydrophobic interactions or reversible covalent bond formation. In this review we discuss the different classes of synthetic receptors for organic ammonium ion recognition and illustrate the scope and limitations of each class with selected examples from the recent literature. The molecular recognition of ammonium ions in amino acids is included and the enantioselective binding of chiral ammonium ions by synthetic receptors is also covered. In our conclusion we compare the strengths and weaknesses of the different types of ammonium ion receptors which may help to select the best approach for specific applications.
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spelling pubmed-28744142010-05-25 Molecular recognition of organic ammonium ions in solution using synthetic receptors Späth, Andreas König, Burkhard Beilstein J Org Chem Review Ammonium ions are ubiquitous in chemistry and molecular biology. Considerable efforts have been undertaken to develop synthetic receptors for their selective molecular recognition. The type of host compounds for organic ammonium ion binding span a wide range from crown ethers to calixarenes to metal complexes. Typical intermolecular interactions are hydrogen bonds, electrostatic and cation–π interactions, hydrophobic interactions or reversible covalent bond formation. In this review we discuss the different classes of synthetic receptors for organic ammonium ion recognition and illustrate the scope and limitations of each class with selected examples from the recent literature. The molecular recognition of ammonium ions in amino acids is included and the enantioselective binding of chiral ammonium ions by synthetic receptors is also covered. In our conclusion we compare the strengths and weaknesses of the different types of ammonium ion receptors which may help to select the best approach for specific applications. Beilstein-Institut 2010-04-06 /pmc/articles/PMC2874414/ /pubmed/20502608 http://dx.doi.org/10.3762/bjoc.6.32 Text en Copyright © 2010, Späth and König https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Review
Späth, Andreas
König, Burkhard
Molecular recognition of organic ammonium ions in solution using synthetic receptors
title Molecular recognition of organic ammonium ions in solution using synthetic receptors
title_full Molecular recognition of organic ammonium ions in solution using synthetic receptors
title_fullStr Molecular recognition of organic ammonium ions in solution using synthetic receptors
title_full_unstemmed Molecular recognition of organic ammonium ions in solution using synthetic receptors
title_short Molecular recognition of organic ammonium ions in solution using synthetic receptors
title_sort molecular recognition of organic ammonium ions in solution using synthetic receptors
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874414/
https://www.ncbi.nlm.nih.gov/pubmed/20502608
http://dx.doi.org/10.3762/bjoc.6.32
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