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Long-term progestin contraceptives (LTPOC) induce aberrant angiogenesis, oxidative stress and apoptosis in the guinea pig uterus: A model for abnormal uterine bleeding in humans

BACKGROUND: Irregular uterine bleeding is the major side effect of, and cause for, discontinuation of long-term progestin-only contraceptives (LTPOCs). The endometria of LTPOC-treated women display abnormally enlarged, fragile blood vessels (BV), decreased endometrial blood flow and oxidative stress...

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Detalles Bibliográficos
Autores principales:	Krikun, Graciela, Buhimschi, Irina A, Hickey, Martha, Schatz, Frederick, Buchwalder, Lynn, Lockwood, Charles J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874514/ https://www.ncbi.nlm.nih.gov/pubmed/20423489 http://dx.doi.org/10.1186/2040-2384-2-8

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