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PTEN Inhibition Improves Muscle Regeneration in Mice Fed a High-Fat Diet

OBJECTIVE: Mechanisms impairing wound healing in diabetes are poorly understood. To identify mechanisms, we induced insulin resistance by chronically feeding mice a high-fat diet (HFD). We also examined the regulation of phosphatidylinositol 3,4,5-trisphosphate (PIP(3)) during muscle regeneration be...

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Detalles Bibliográficos
Autores principales:	Hu, Zhaoyong, Wang, Huiling, Lee, In Hee, Modi, Swati, Wang, Xiaonan, Du, Jie, Mitch, William E.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2010
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874691/ https://www.ncbi.nlm.nih.gov/pubmed/20200318 http://dx.doi.org/10.2337/db09-1155

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