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TBC1D1 Regulates Insulin- and Contraction-Induced Glucose Transport in Mouse Skeletal Muscle

OBJECTIVE: TBC1D1 is a member of the TBC1 Rab-GTPase family of proteins and is highly expressed in skeletal muscle. Insulin and contraction increase TBC1D1 phosphorylation on phospho-Akt substrate motifs (PASs), but the function of TBC1D1 in muscle is not known. Genetic linkage analyses show a TBC1D...

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Detalles Bibliográficos
Autores principales:	An, Ding, Toyoda, Taro, Taylor, Eric B., Yu, Haiyan, Fujii, Nobuharu, Hirshman, Michael F., Goodyear, Laurie J.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2010
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874696/ https://www.ncbi.nlm.nih.gov/pubmed/20299473 http://dx.doi.org/10.2337/db09-1266

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