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Caspase Inhibitor Therapy Synergizes With Costimulation Blockade to Promote Indefinite Islet Allograft Survival
OBJECTIVE: Costimulation blockade has emerged as a selective nontoxic maintenance therapy in transplantation. However, these drugs must be combined with other immunomodulatory agents to ensure long-term graft survival. RESEARCH DESIGN AND METHODS: Recent work has demonstrated that caspase inhibitor...
Autores principales: | Emamaullee, Juliet A., Davis, Joy, Pawlick, Rena, Toso, Christian, Merani, Shaheed, Cai, Sui-Xiong, Tseng, Ben, Shapiro, A.M. James |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874708/ https://www.ncbi.nlm.nih.gov/pubmed/20332344 http://dx.doi.org/10.2337/db09-0502 |
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