Cargando…

Extracellular Fatty Acid Synthase: A Possible Surrogate Biomarker of Insulin Resistance

CONTEXT: Circulating fatty acid synthase (FASN) is a biomarker of metabolically demanding human diseases. The aim of this study was to determine whether circulating FASN could be a biomarker of overnutrition-induced metabolic stress and insulin resistance in common metabolic disorders. RESEARCH DESI...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fernandez-Real, Jose Manuel, Menendez, Javier A., Moreno-Navarrete, Jose Maria, Blüher, Matthias, Vazquez-Martin, Alejandro, Vázquez, María Jesús, Ortega, Francisco, Diéguez, Carlos, Frühbeck, Gema, Ricart, Wifredo, Vidal-Puig, Antonio
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2010
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874712/ https://www.ncbi.nlm.nih.gov/pubmed/20299470 http://dx.doi.org/10.2337/db09-1756

Ejemplares similares

Serum HER-2 concentration is associated with insulin resistance and decreases after weight loss
por: Fernández-Real, José Manuel, et al.
Publicado: (2010)

Circulating omentin concentration increases after weight loss
por: Moreno-Navarrete, José María, et al.
Publicado: (2010)

Increased adipose tissue heme levels and exportation are associated with altered systemic glucose metabolism
por: Moreno-Navarrete, José María, et al.
Publicado: (2017)

Complement Factor H Is Expressed in Adipose Tissue in Association With Insulin Resistance
por: Moreno-Navarrete, José María, et al.
Publicado: (2010)

Study of caveolin-1 gene expression in whole adipose tissue and its subfractions and during differentiation of human adipocytes
por: Fernández-Real, José M, et al.
Publicado: (2010)

Iron and Obesity Status-Associated Insulin Resistance Influence Circulating Fibroblast-Growth Factor-23 Concentrations
por: Fernández-Real, José Manuel, et al.
Publicado: (2013)

Circulating Tryptase as a Marker for Subclinical Atherosclerosis in Obese Subjects
por: Moreno, María, et al.
Publicado: (2014)

Permanent cystathionine-β-Synthase gene knockdown promotes inflammation and oxidative stress in immortalized human adipose-derived mesenchymal stem cells, enhancing their adipogenic capacity
por: Comas, Ferran, et al.
Publicado: (2020)

Circulating Zonulin, a Marker of Intestinal Permeability, Is Increased in Association with Obesity-Associated Insulin Resistance
por: Moreno-Navarrete, José María, et al.
Publicado: (2012)

Adipocytokines and Insulin Resistance: The possible role of lipocalin-2, retinol binding protein-4, and adiponectin
por: Esteve, Eduardo, et al.
Publicado: (2009)

Lactoferrin gene knockdown leads to similar effects to iron chelation in human adipocytes
por: Moreno-Navarrete, José María, et al.
Publicado: (2014)

Breast Cancer 1 (BrCa1) May Be behind Decreased Lipogenesis in Adipose Tissue from Obese Subjects
por: Ortega, Francisco J., et al.
Publicado: (2012)

Circulating Retinol-Binding Protein-4 Concentration Might Reflect Insulin Resistance–Associated Iron Overload
por: Fernández-Real, José Manuel, et al.
Publicado: (2008)

OCT1 Expression in Adipocytes Could Contribute to Increased Metformin Action in Obese Subjects
por: Moreno-Navarrete, José María, et al.
Publicado: (2011)

Inflammation triggers specific microRNA profiles in human adipocytes and macrophages and in their supernatants
por: Ortega, Francisco José, et al.
Publicado: (2015)

The MRC1/CD68 Ratio Is Positively Associated with Adipose Tissue Lipogenesis and with Muscle Mitochondrial Gene Expression in Humans
por: Moreno-Navarrete, José María, et al.
Publicado: (2013)

Surfactant Protein D, a Marker of Lung Innate Immunity, Is Positively Associated With Insulin Sensitivity
por: Fernández-Real, José Manuel, et al.
Publicado: (2010)

Circulating Irisin Levels Are Positively Associated with Metabolic Risk Factors in Sedentary Subjects
por: Moreno, María, et al.
Publicado: (2015)

Circulating Irisin and Myostatin as Markers of Muscle Strength and Physical Condition in Elderly Subjects
por: Planella-Farrugia, Cristina, et al.
Publicado: (2019)

Decreased RB1 mRNA, Protein, and Activity Reflect Obesity-Induced Altered Adipogenic Capacity in Human Adipose Tissue
por: Moreno-Navarrete, José María, et al.
Publicado: (2013)

Neuregulin 4 Is a Novel Marker of Beige Adipocyte Precursor Cells in Human Adipose Tissue
por: Comas, Ferran, et al.
Publicado: (2019)

Low serum mannose-binding lectin are associated with inflammation, new-onset diabetes mellitus and subclinical rejection after renal transplantation
por: Moreso, Francesc, et al.
Publicado: (2011)

Platelet count and Interleukin 6 Gene polymorphism in healthy subjects
por: Fernandez-Real, José-Manuel, et al.
Publicado: (2001)

MiRNA Expression Profile of Human Subcutaneous Adipose and during Adipocyte Differentiation
por: Ortega, Francisco J., et al.
Publicado: (2010)

Specific adipose tissue Lbp gene knockdown prevents diet-induced body weight gain, impacting fat accretion-related gene and protein expression
por: Latorre, Jessica, et al.
Publicado: (2022)

Serum neuregulin 4 is negatively correlated with insulin sensitivity in humans and impairs mitochondrial respiration in HepG2 cells
por: Martínez, Cristina, et al.
Publicado: (2022)

The l-α-Lysophosphatidylinositol/GPR55 System and Its Potential Role in Human Obesity
por: Moreno-Navarrete, José María, et al.
Publicado: (2012)

Common Genetic Variants of Surfactant Protein-D (SP-D) Are Associated with Type 2 Diabetes
por: Pueyo, Neus, et al.
Publicado: (2013)

Iron status influences non-alcoholic fatty liver disease in obesity through the gut microbiome
por: Mayneris-Perxachs, Jordi, et al.
Publicado: (2021)

Multiple Hürthle cell adenomas in a patient with thyroid hormone resistance
por: Xifra, Gemma, et al.
Publicado: (2013)

Impact of Nutritional Changes on Nonalcoholic Fatty Liver Disease
por: Perdomo, Carolina M., et al.
Publicado: (2019)

Uncovering Suitable Reference Proteins for Expression Studies in Human Adipose Tissue with Relevance to Obesity
por: Pérez-Pérez, Rafael, et al.
Publicado: (2012)

Neuregulin 4 Downregulation Induces Insulin Resistance in 3T3-L1 Adipocytes through Inflammation and Autophagic Degradation of GLUT4 Vesicles
por: Díaz-Sáez, Francisco, et al.
Publicado: (2021)

Circulating Fatty Acid Synthase in pregnant women: Relationship to blood pressure, maternal metabolism and newborn parameters
por: Carreras-Badosa, Gemma, et al.
Publicado: (2016)

Phylogenetic analysis of homologous fatty acid synthase and polyketide synthase involved in aflatoxin biosynthesis
por: Marcet-Houben, Marina, et al.
Publicado: (2008)

Impaired Plakophilin-2 in obesity breaks cell cycle dynamics to breed adipocyte senescence
por: Lluch, Aina, et al.
Publicado: (2023)

Gut bacterial ClpB-like gene function is associated with decreased body weight and a characteristic microbiota profile
por: Arnoriaga-Rodríguez, María, et al.
Publicado: (2020)

Deletion of Inducible Nitric-Oxide Synthase in Leptin-Deficient Mice Improves Brown Adipose Tissue Function
por: Becerril, Sara, et al.
Publicado: (2010)

CD14 Modulates Inflammation-Driven Insulin Resistance
por: Fernández-Real, José Manuel, et al.
Publicado: (2011)

Compounds that modulate AMPK activity and hepatic steatosis impact the biosynthesis of microRNAs required to maintain lipid homeostasis in hepatocytes
por: Latorre, Jèssica, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_6ftoj235nutc6qcjag640jd5ea