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Efficient conditional and promoter-specific in vivo expression of cDNAs of choice by taking advantage of recombinase-mediated cassette exchange using FlEx gene traps
Recombinase-mediated cassette exchange (RMCE) exploits the possibility to unidirectionally exchange any genetic material flanked by heterotypic recombinase recognition sites (RRS) with target sites in the genome. Due to a limited number of available pre-fabricated target sites, RMCE in mouse embryon...
Autores principales: | Schebelle, Laura, Wolf, Claudia, Stribl, Carola, Javaheri, Tahereh, Schnütgen, Frank, Ettinger, Andreas, Ivics, Zoltán, Hansen, Jens, Ruiz, Patricia, von Melchner, Harald, Wurst, Wolfgang, Floss, Thomas |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875000/ https://www.ncbi.nlm.nih.gov/pubmed/20139417 http://dx.doi.org/10.1093/nar/gkq044 |
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