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DNA chirality-dependent stimulation of topoisomerase IV activity by the C-terminal AAA+ domain of FtsK
We have studied the stimulation of topoisomerase IV (Topo IV) by the C-terminal AAA+ domain of FtsK. These two proteins combine to assure proper chromosome segregation in the cell. Stimulation of Topo IV activity was dependent on the chirality of the DNA substrate: FtsK stimulated decatenation of ca...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875013/ https://www.ncbi.nlm.nih.gov/pubmed/20081205 http://dx.doi.org/10.1093/nar/gkp1243 |