Pronuclear transfer in human embryos to prevent transmission of mitochondrial DNA disease

Mitochondrial DNA (mtDNA) mutations are a common cause of genetic disease with pathogenic mtDNA mutations being detected in approximately 1 in 250 live births1-3 and at least 1 in 10,000 adults in the UK affected by mtDNA disease4. Treatment options for patients with mtDNA disease are extremely limi...

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Detalles Bibliográficos
Autores principales: Craven, Lyndsey, Tuppen, Helen A, Greggains, Gareth D, Harbottle, Stephen J, Murphy, Julie L, Cree, Lynsey M, Murdoch, Alison P, Chinnery, Patrick F, Taylor, Robert W, Lightowlers, Robert N, Herbert, Mary, Turnbull, Douglass M
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875160/
https://www.ncbi.nlm.nih.gov/pubmed/20393463
http://dx.doi.org/10.1038/nature08958

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