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Regulation of p53 expression, phosphorylation and sub-cellular localisation by a G-protein coupled receptor

G-protein coupled receptors (GPCRs) have been extremely successful drug targets for a multitude of diseases from heart failure to depression. This super-family of cell surface receptors have not, however, been widely considered as a viable target in cancer treatment. In the current study we demonstr...

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Detalles Bibliográficos
Autores principales: Solyakov, Lev, Sayan, Emre, Riley, Joan, Pointon, Amy, Tobin, Andrew B
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875175/
https://www.ncbi.nlm.nih.gov/pubmed/19648965
http://dx.doi.org/10.1038/onc.2009.225