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High expression of BCL-2 predicts favorable outcome in non-small cell lung cancer patients with non squamous histology

BACKGROUND: Bcl-2 promotes cell survival by inhibiting adapters needed for the activation and cleavage of caspases thus blocking the proteolytic cascade that ultimately dismantles the cell. Bcl-2 has been investigated as a prognostic factor in non small cell lung cancer (NSCLC) patients with conflic...

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Detalles Bibliográficos
Autores principales:	Anagnostou, Valsamo K, Lowery, Frank J, Zolota, Vassiliki, Tzelepi, Vassiliki, Gopinath, Arun, Liceaga, Camil, Panagopoulos, Nikolaos, Frangia, Konstantina, Tanoue, Lynn, Boffa, Daniel, Gettinger, Scott, Detterbeck, Frank, Homer, Robert J, Dougenis, Dimitrios, Rimm, David L, Syrigos, Konstantinos N
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875218/ https://www.ncbi.nlm.nih.gov/pubmed/20459695 http://dx.doi.org/10.1186/1471-2407-10-186

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