B7-H1-Deficiency Enhances the Potential of Tolerogenic Dendritic Cells by Activating CD1d-Restricted Type II NKT Cells

BACKGROUND: Dendritic cells (DC) can act tolerogenic at a semi-mature stage by induction of protective CD4(+) T cell and NKT cell responses. METHODOLOGY/PRINCIPAL FINDINGS: Here we studied the role of the co-inhibitory molecule B7-H1 (PD-L1, CD274) on semi-mature DC that were generated from bone mar...

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Detalles Bibliográficos
Autores principales: Brandl, Carolin, Ortler, Sonja, Herrmann, Thomas, Cardell, Susanna, Lutz, Manfred B., Wiendl, Heinz
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875405/
https://www.ncbi.nlm.nih.gov/pubmed/20520738
http://dx.doi.org/10.1371/journal.pone.0010800

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