Hyperglycemia-Induced Platelet Activation in Type 2 Diabetes Is Resistant to Aspirin but Not to a Nitric Oxide–Donating Agent

OBJECTIVE: Acute, short-term hyperglycemia enhances high shear stress–induced platelet activation in type 2 diabetes. Several observations suggest that platelets in type 2 diabetes are resistant to inhibition by aspirin. Our aim was to assess comparatively the effect of aspirin, a nitric oxide–donat...

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Detalles Bibliográficos
Autores principales: Gresele, Paolo, Marzotti, Stefania, Guglielmini, Giuseppe, Momi, Stefania, Giannini, Silvia, Minuz, Pietro, Lucidi, Paola, Bolli, Geremia B.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875435/
https://www.ncbi.nlm.nih.gov/pubmed/20299485
http://dx.doi.org/10.2337/dc09-2013

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