Increased blood flow by insulin infusion targeting normoglycemia in patients with severe sepsis: friend or foe?

A small study in patients with severe sepsis suggested that insulin infused to normalize blood glucose levels increased forearm flow. This clinical observation supports the effect of insulin on the endothelium, as previously shown by in vitro studies and by in vivo animal models of critical illness,...

Descripción completa

Detalles Bibliográficos
Autor principal: Berghe, Greet Van den
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875501/
https://www.ncbi.nlm.nih.gov/pubmed/20236504
http://dx.doi.org/10.1186/cc8228
_version_ 1782181586757746688
author Berghe, Greet Van den
author_facet Berghe, Greet Van den
author_sort Berghe, Greet Van den
collection PubMed
description A small study in patients with severe sepsis suggested that insulin infused to normalize blood glucose levels increased forearm flow. This clinical observation supports the effect of insulin on the endothelium, as previously shown by in vitro studies and by in vivo animal models of critical illness, but the clinical consequences remain unclear.
format Text
id pubmed-2875501
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-28755012011-02-16 Increased blood flow by insulin infusion targeting normoglycemia in patients with severe sepsis: friend or foe? Berghe, Greet Van den Crit Care Commentary A small study in patients with severe sepsis suggested that insulin infused to normalize blood glucose levels increased forearm flow. This clinical observation supports the effect of insulin on the endothelium, as previously shown by in vitro studies and by in vivo animal models of critical illness, but the clinical consequences remain unclear. BioMed Central 2010 2010-02-16 /pmc/articles/PMC2875501/ /pubmed/20236504 http://dx.doi.org/10.1186/cc8228 Text en Copyright ©2010 BioMed Central Ltd
spellingShingle Commentary
Berghe, Greet Van den
Increased blood flow by insulin infusion targeting normoglycemia in patients with severe sepsis: friend or foe?
title Increased blood flow by insulin infusion targeting normoglycemia in patients with severe sepsis: friend or foe?
title_full Increased blood flow by insulin infusion targeting normoglycemia in patients with severe sepsis: friend or foe?
title_fullStr Increased blood flow by insulin infusion targeting normoglycemia in patients with severe sepsis: friend or foe?
title_full_unstemmed Increased blood flow by insulin infusion targeting normoglycemia in patients with severe sepsis: friend or foe?
title_short Increased blood flow by insulin infusion targeting normoglycemia in patients with severe sepsis: friend or foe?
title_sort increased blood flow by insulin infusion targeting normoglycemia in patients with severe sepsis: friend or foe?
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875501/
https://www.ncbi.nlm.nih.gov/pubmed/20236504
http://dx.doi.org/10.1186/cc8228
work_keys_str_mv AT berghegreetvanden increasedbloodflowbyinsulininfusiontargetingnormoglycemiainpatientswithseveresepsisfriendorfoe

Ejemplares similares