A peptidyl-glucosamine derivative affects IKKα kinase activity in human chondrocytes

INTRODUCTION: Nuclear factor-κB (NF-κB) transcription factor regulates several cell signaling pathways, such as differentiation and inflammation, which are both altered in osteoarthritis. Inhibitor κB kinase (IKK)α and IKKβ are kinases involved in the activation of the NF-κB transcription factor. Th...

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Detalles Bibliográficos
Autores principales: Scotto d'Abusco, Anna, Politi, Laura, Giordano, Cesare, Scandurra, Roberto
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875647/
https://www.ncbi.nlm.nih.gov/pubmed/20113495
http://dx.doi.org/10.1186/ar2920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875647/
https://www.ncbi.nlm.nih.gov/pubmed/20113495
http://dx.doi.org/10.1186/ar2920

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