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A peptidyl-glucosamine derivative affects IKKα kinase activity in human chondrocytes
INTRODUCTION: Nuclear factor-κB (NF-κB) transcription factor regulates several cell signaling pathways, such as differentiation and inflammation, which are both altered in osteoarthritis. Inhibitor κB kinase (IKK)α and IKKβ are kinases involved in the activation of the NF-κB transcription factor. Th...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875647/ https://www.ncbi.nlm.nih.gov/pubmed/20113495 http://dx.doi.org/10.1186/ar2920 |