c-Fms-mediated differentiation and priming of monocyte lineage cells play a central role in autoimmune arthritis

INTRODUCTION: Tyrosine kinases are key mediators of multiple signaling pathways implicated in rheumatoid arthritis (RA). We previously demonstrated that imatinib mesylate--a Food and Drug Administration (FDA)-approved, antineoplastic drug that potently inhibits the tyrosine kinases Abl, c-Kit, plate...

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Detalles Bibliográficos
Autores principales: Paniagua, Ricardo T, Chang, Anna, Mariano, Melissa M, Stein, Emily A, Wang, Qian, Lindstrom, Tamsin M, Sharpe, Orr, Roscow, Claire, Ho, Peggy P, Lee, David M, Robinson, William H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875666/
https://www.ncbi.nlm.nih.gov/pubmed/20181277
http://dx.doi.org/10.1186/ar2940

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