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Stc1: A Critical Link between RNAi and Chromatin Modification Required for Heterochromatin Integrity
In fission yeast, RNAi directs heterochromatin formation at centromeres, telomeres, and the mating type locus. Noncoding RNAs transcribed from repeat elements generate siRNAs that are incorporated into the Argonaute-containing RITS complex and direct it to nascent homologous transcripts. This leads...
Autores principales: | Bayne, Elizabeth H., White, Sharon A., Kagansky, Alexander, Bijos, Dominika A., Sanchez-Pulido, Luis, Hoe, Kwang-Lae, Kim, Dong-Uk, Park, Han-Oh, Ponting, Chris P., Rappsilber, Juri, Allshire, Robin C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875855/ https://www.ncbi.nlm.nih.gov/pubmed/20211136 http://dx.doi.org/10.1016/j.cell.2010.01.038 |
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