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Proton pump inhibitors as anti vacuolar-ATPases drugs: a novel anticancer strategy
The vacuolar ATPases are ATP-dependent proton pumps whose functions include the acidification of intracellular compartments and the extrusion of protons through the cell cytoplasmic membrane. These pumps play a pivotal role in the regulation of cell pH in normal cells and, to a much greater extent,...
Autores principales: | Spugnini, Enrico P, Citro, Gennaro, Fais, Stefano |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876100/ https://www.ncbi.nlm.nih.gov/pubmed/20459683 http://dx.doi.org/10.1186/1756-9966-29-44 |
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