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Validation of a mouse xenograft model system for gene expression analysis of human acute lymphoblastic leukaemia
BACKGROUND: Pre-clinical models that effectively recapitulate human disease are critical for expanding our knowledge of cancer biology and drug resistance mechanisms. For haematological malignancies, the non-obese diabetic/severe combined immunodeficient (NOD/SCID) mouse is one of the most successfu...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876122/ https://www.ncbi.nlm.nih.gov/pubmed/20406497 http://dx.doi.org/10.1186/1471-2164-11-256 |