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A statistical method for excluding non-variable CpG sites in high-throughput DNA methylation profiling
BACKGROUND: High-throughput DNA methylation arrays are likely to accelerate the pace of methylation biomarker discovery for a wide variety of diseases. A potential problem with a standard set of probes measuring the methylation status of CpG sites across the whole genome is that many sites may not s...
Autores principales: | Meng, Hailong, Joyce, Andrew R, Adkins, Daniel E, Basu, Priyadarshi, Jia, Yankai, Li, Guoya, Sengupta, Tapas K, Zedler, Barbara K, Murrelle, E Lenn, van den Oord, Edwin JCG |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876131/ https://www.ncbi.nlm.nih.gov/pubmed/20441598 http://dx.doi.org/10.1186/1471-2105-11-227 |
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