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A unique adolescent response to reward prediction errors

Previous work has demonstrated that human adolescents may be hypersensitive to rewards; it is unknown which aspect of reward processing this reflects. We separated decision value and prediction error signals and found that neural prediction error signals in the striatum peaked in adolescence, wherea...

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Detalles Bibliográficos
Autores principales: Cohen, Jessica R., Asarnow, Robert F., Sabb, Fred W., Bilder, Robert M., Bookheimer, Susan Y., Knowlton, Barbara J., Poldrack, Russell A.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876211/
https://www.ncbi.nlm.nih.gov/pubmed/20473290
http://dx.doi.org/10.1038/nn.2558
Descripción
Sumario:Previous work has demonstrated that human adolescents may be hypersensitive to rewards; it is unknown which aspect of reward processing this reflects. We separated decision value and prediction error signals and found that neural prediction error signals in the striatum peaked in adolescence, whereas neural decision value signals varied depending upon how value was modeled. This suggests that one contributor to adolescent reward-seeking may be heightened dopaminergic prediction error responsivity.