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MHC I Stabilizing Potential of Computer-Designed Octapeptides

Experimental results are presented for 180 in silico designed octapeptide sequences and their stabilizing effects on the major histocompatibility class I molecule H-2K(b). Peptide sequence design was accomplished by a combination of an ant colony optimization algorithm with artificial neural network...

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Detalles Bibliográficos
Autores principales: Wisniewska, Joanna M., Jäger, Natalie, Freier, Anja, Losch, Florian O., Wiesmüller, Karl-Heinz, Walden, Peter, Wrede, Paul, Schneider, Gisbert, Hiss, Jan A.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876253/
https://www.ncbi.nlm.nih.gov/pubmed/20508831
http://dx.doi.org/10.1155/2010/396847