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Swine Workers and Swine Influenza Virus Infections

In 2004, 803 rural Iowans from the Agricultural Health Study were enrolled in a 2-year prospective study of zoonotic influenza transmission. Demographic and occupational exposure data from enrollment, 12-month, and 24-month follow-up encounters were examined for association with evidence of previous...

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Autores principales: Gray, Gregory C., McCarthy, Troy, Capuano, Ana W., Setterquist, Sharon F., Olsen, Christopher W., Alavanja, Michael C., Lynch, Charles F.
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876739/
https://www.ncbi.nlm.nih.gov/pubmed/18258038
http://dx.doi.org/10.3201/eid1312.061323
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author Gray, Gregory C.
McCarthy, Troy
Capuano, Ana W.
Setterquist, Sharon F.
Olsen, Christopher W.
Alavanja, Michael C.
Lynch, Charles F.
author_facet Gray, Gregory C.
McCarthy, Troy
Capuano, Ana W.
Setterquist, Sharon F.
Olsen, Christopher W.
Alavanja, Michael C.
Lynch, Charles F.
author_sort Gray, Gregory C.
collection PubMed
description In 2004, 803 rural Iowans from the Agricultural Health Study were enrolled in a 2-year prospective study of zoonotic influenza transmission. Demographic and occupational exposure data from enrollment, 12-month, and 24-month follow-up encounters were examined for association with evidence of previous and incident influenza virus infections. When proportional odds modeling with multivariable adjustment was used, upon enrollment, swine-exposed participants (odds ratio [OR] 54.9, 95% confidence interval [CI] 13.0–232.6) and their nonswine-exposed spouses (OR 28.2, 95% CI 6.1–130.1) were found to have an increased odds of elevated antibody level to swine influenza (H1N1) virus compared with 79 nonexposed University of Iowa personnel. Further evidence of occupational swine influenza virus infections was observed through self-reported influenza-like illness data, comparisons of enrollment and follow-up serum samples, and the isolation of a reassortant swine influenza (H1N1) virus from an ill swine farmer. Study data suggest that swine workers and their nonswine-exposed spouses are at increased risk of zoonotic influenza virus infections.
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spelling pubmed-28767392010-06-01 Swine Workers and Swine Influenza Virus Infections Gray, Gregory C. McCarthy, Troy Capuano, Ana W. Setterquist, Sharon F. Olsen, Christopher W. Alavanja, Michael C. Lynch, Charles F. Emerg Infect Dis Research In 2004, 803 rural Iowans from the Agricultural Health Study were enrolled in a 2-year prospective study of zoonotic influenza transmission. Demographic and occupational exposure data from enrollment, 12-month, and 24-month follow-up encounters were examined for association with evidence of previous and incident influenza virus infections. When proportional odds modeling with multivariable adjustment was used, upon enrollment, swine-exposed participants (odds ratio [OR] 54.9, 95% confidence interval [CI] 13.0–232.6) and their nonswine-exposed spouses (OR 28.2, 95% CI 6.1–130.1) were found to have an increased odds of elevated antibody level to swine influenza (H1N1) virus compared with 79 nonexposed University of Iowa personnel. Further evidence of occupational swine influenza virus infections was observed through self-reported influenza-like illness data, comparisons of enrollment and follow-up serum samples, and the isolation of a reassortant swine influenza (H1N1) virus from an ill swine farmer. Study data suggest that swine workers and their nonswine-exposed spouses are at increased risk of zoonotic influenza virus infections. Centers for Disease Control and Prevention 2007-12 /pmc/articles/PMC2876739/ /pubmed/18258038 http://dx.doi.org/10.3201/eid1312.061323 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Gray, Gregory C.
McCarthy, Troy
Capuano, Ana W.
Setterquist, Sharon F.
Olsen, Christopher W.
Alavanja, Michael C.
Lynch, Charles F.
Swine Workers and Swine Influenza Virus Infections
title Swine Workers and Swine Influenza Virus Infections
title_full Swine Workers and Swine Influenza Virus Infections
title_fullStr Swine Workers and Swine Influenza Virus Infections
title_full_unstemmed Swine Workers and Swine Influenza Virus Infections
title_short Swine Workers and Swine Influenza Virus Infections
title_sort swine workers and swine influenza virus infections
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876739/
https://www.ncbi.nlm.nih.gov/pubmed/18258038
http://dx.doi.org/10.3201/eid1312.061323
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