Studies of Reservoir Hosts for Marburg Virus

To determine reservoir hosts for Marburg virus (MARV), we examined the fauna of a mine in northeastern Democratic Republic of the Congo. The mine was associated with a protracted outbreak of Marburg hemorrhagic fever during 1998–2000. We found MARV nucleic acid in 12 bats, comprising 3.0%–3.6% of 2...

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Detalles Bibliográficos
Autores principales: Swanepoel, Robert, Smit, Sheilagh B., Rollin, Pierre E., Formenty, Pierre, Leman, Patricia A., Kemp, Alan, Burt, Felicity J., Grobbelaar, Antoinette A., Croft, Janice, Bausch, Daniel G., Zeller, Hervé, Leirs, Herwig, Braack, L.E.O., Libande, Modeste L., Zaki, Sherif, Nichol, Stuart T., Ksiazek, Thomas G., Paweska, Janusz T.
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876776/
https://www.ncbi.nlm.nih.gov/pubmed/18258034
http://dx.doi.org/10.3201/eid1312.071115
Descripción
Sumario:To determine reservoir hosts for Marburg virus (MARV), we examined the fauna of a mine in northeastern Democratic Republic of the Congo. The mine was associated with a protracted outbreak of Marburg hemorrhagic fever during 1998–2000. We found MARV nucleic acid in 12 bats, comprising 3.0%–3.6% of 2 species of insectivorous bat and 1 species of fruit bat. We found antibody to the virus in the serum of 9.7% of 1 of the insectivorous species and in 20.5% of the fruit bat species, but attempts to isolate virus were unsuccessful.

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