Chromosome copy number changes carry prognostic information independent of KIT/PDGFRA point mutations in gastrointestinal stromal tumors

BACKGROUND: Oncogenic point mutations in KIT or PDGFRA are recognized as the primary events responsible for the pathogenesis of most gastrointestinal stromal tumors (GIST), but additional genomic alterations are frequent and presumably required for tumor progression. The relative contribution of suc...

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Detalles Bibliográficos
Autores principales: Silva, Mara, Veiga, Isabel, Ribeiro, Franclim R, Vieira, Joana, Pinto, Carla, Pinheiro, Manuela, Mesquita, Bárbara, Santos, Catarina, Soares, Marta, Dinis, José, Santos, Lúcio, Lopes, Paula, Afonso, Mariana, Lopes, Carlos, Teixeira, Manuel R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876987/
https://www.ncbi.nlm.nih.gov/pubmed/20470368
http://dx.doi.org/10.1186/1741-7015-8-26

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