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HSF1 overexpression enhances oncolytic effect of replicative adenovirus
BACKGROUND: E1B55kD deleted oncolytic adenovirus was designed to achieve cancer-specific cytotoxicity, but showed limitations in clinical study. To find a method to increase its efficacy, we investigated the correlation between oncolytic effect of such oncolytic adenovirus Adel55 and intracellular h...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877000/ https://www.ncbi.nlm.nih.gov/pubmed/20459615 http://dx.doi.org/10.1186/1479-5876-8-44 |