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Spatio-temporal modeling of signaling protein recruitment to EGFR
BACKGROUND: A stochastic simulator was implemented to study EGFR signal initiation in 3D with single molecule detail. The model considers previously unexplored contributions to receptor-adaptor coupling, such as receptor clustering and diffusive properties of both receptors and binding partners. The...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877007/ https://www.ncbi.nlm.nih.gov/pubmed/20459599 http://dx.doi.org/10.1186/1752-0509-4-57 |