Pediatric Hemophagocytic Syndromes: A Diagnostic and Therapeutic Challenge

Pediatric hemophagocytic syndrome (HS) is a severe and often fatal clinical disorder. This syndrome is frequently unrecognized, and thus, affected children may receive suboptimal management, leading to an increase in mortality. The purpose of this review is to provide a clinical guide to (1) the rec...

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Detalles Bibliográficos
Autores principales: Jabado, Nada, McCusker, Christine, Basile, Genevieve de Saint
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877072/
https://www.ncbi.nlm.nih.gov/pubmed/20529219
http://dx.doi.org/10.1186/1710-1492-1-4-142
Descripción
Sumario:Pediatric hemophagocytic syndrome (HS) is a severe and often fatal clinical disorder. This syndrome is frequently unrecognized, and thus, affected children may receive suboptimal management, leading to an increase in mortality. The purpose of this review is to provide a clinical guide to (1) the recognition of HS based on clinical, biologic, and pathologic features; (2) the identification of the primary cause of HS in a given affected child; and (3) the initiation of effective treatment in a timely manner.

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