Pediatric Hemophagocytic Syndromes: A Diagnostic and Therapeutic Challenge

Pediatric hemophagocytic syndrome (HS) is a severe and often fatal clinical disorder. This syndrome is frequently unrecognized, and thus, affected children may receive suboptimal management, leading to an increase in mortality. The purpose of this review is to provide a clinical guide to (1) the rec...

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Detalles Bibliográficos
Autores principales: Jabado, Nada, McCusker, Christine, Basile, Genevieve de Saint
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877072/
https://www.ncbi.nlm.nih.gov/pubmed/20529219
http://dx.doi.org/10.1186/1710-1492-1-4-142
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author Jabado, Nada
McCusker, Christine
Basile, Genevieve de Saint
author_facet Jabado, Nada
McCusker, Christine
Basile, Genevieve de Saint
author_sort Jabado, Nada
collection PubMed
description Pediatric hemophagocytic syndrome (HS) is a severe and often fatal clinical disorder. This syndrome is frequently unrecognized, and thus, affected children may receive suboptimal management, leading to an increase in mortality. The purpose of this review is to provide a clinical guide to (1) the recognition of HS based on clinical, biologic, and pathologic features; (2) the identification of the primary cause of HS in a given affected child; and (3) the initiation of effective treatment in a timely manner.
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spelling pubmed-28770722010-05-27 Pediatric Hemophagocytic Syndromes: A Diagnostic and Therapeutic Challenge Jabado, Nada McCusker, Christine Basile, Genevieve de Saint Allergy Asthma Clin Immunol Review Pediatric hemophagocytic syndrome (HS) is a severe and often fatal clinical disorder. This syndrome is frequently unrecognized, and thus, affected children may receive suboptimal management, leading to an increase in mortality. The purpose of this review is to provide a clinical guide to (1) the recognition of HS based on clinical, biologic, and pathologic features; (2) the identification of the primary cause of HS in a given affected child; and (3) the initiation of effective treatment in a timely manner. BioMed Central 2005-12-15 /pmc/articles/PMC2877072/ /pubmed/20529219 http://dx.doi.org/10.1186/1710-1492-1-4-142 Text en
spellingShingle Review
Jabado, Nada
McCusker, Christine
Basile, Genevieve de Saint
Pediatric Hemophagocytic Syndromes: A Diagnostic and Therapeutic Challenge
title Pediatric Hemophagocytic Syndromes: A Diagnostic and Therapeutic Challenge
title_full Pediatric Hemophagocytic Syndromes: A Diagnostic and Therapeutic Challenge
title_fullStr Pediatric Hemophagocytic Syndromes: A Diagnostic and Therapeutic Challenge
title_full_unstemmed Pediatric Hemophagocytic Syndromes: A Diagnostic and Therapeutic Challenge
title_short Pediatric Hemophagocytic Syndromes: A Diagnostic and Therapeutic Challenge
title_sort pediatric hemophagocytic syndromes: a diagnostic and therapeutic challenge
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877072/
https://www.ncbi.nlm.nih.gov/pubmed/20529219
http://dx.doi.org/10.1186/1710-1492-1-4-142
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AT mccuskerchristine pediatrichemophagocyticsyndromesadiagnosticandtherapeuticchallenge
AT basilegenevievedesaint pediatrichemophagocyticsyndromesadiagnosticandtherapeuticchallenge

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