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Knockout of the Bcmo1 gene results in an inflammatory response in female lung, which is suppressed by dietary beta-carotene

Beta-carotene 15,15′-monooxygenase 1 knockout (Bcmo1 (−/−)) mice accumulate beta-carotene (BC) similarly to humans, whereas wild-type (Bcmo1 (+/+)) mice efficiently cleave BC. Bcmo1 (−/−) mice are therefore suitable to investigate BC-induced alterations in gene expression in lung, assessed by microa...

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Detalles Bibliográficos
Autores principales:	van Helden, Yvonne G. J., Heil, Sandra G., van Schooten, Frederik J., Kramer, Evelien, Hessel, Susanne, Amengual, Jaume, Ribot, Joan, Teerds, Katja, Wyss, Adrian, Lietz, Georg, Bonet, M. Luisa, von Lintig, Johannes, Godschalk, Roger W. L., Keijer, Jaap
Formato:	Texto
Lenguaje:	English
Publicado:	SP Birkhäuser Verlag Basel 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877315/ https://www.ncbi.nlm.nih.gov/pubmed/20372966 http://dx.doi.org/10.1007/s00018-010-0341-7

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