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RNF-121 Is an Endoplasmic Reticulum-Membrane E3 Ubiquitin Ligase Involved in the Regulation of β-Integrin

We report on the characterization of RNF-121, an evolutionarily conserved E3 ligase RING finger protein that is expressed in the endoplasmic reticulum (ER) of various cells and tissues in Caenorhabditis elegans. Inactivation of RNF-121 induced an elevation in BiP expression and increased the sensiti...

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Detalles Bibliográficos
Autores principales: Darom, Amir, Bening-Abu-Shach, Ulrike, Broday, Limor
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877638/
https://www.ncbi.nlm.nih.gov/pubmed/20357004
http://dx.doi.org/10.1091/mbc.E09-09-0774