Cargando…

Additive effects of LPL, APOA5 and APOE variant combinations on triglyceride levels and hypertriglyceridemia: results of the ICARIA genetic sub-study

BACKGROUND: Hypertriglyceridemia (HTG) is a well-established independent risk factor for cardiovascular disease and the influence of several genetic variants in genes related with triglyceride (TG) metabolism has been described, including LPL, APOA5 and APOE. The combined analysis of these polymorph...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ariza, María-José, Sánchez-Chaparro, Miguel-Ángel, Barón, Francisco-Javier, Hornos, Ana-María, Calvo-Bonacho, Eva, Rioja, José, Valdivielso, Pedro, Gelpi, José-Antonio, González-Santos, Pedro
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877669/ https://www.ncbi.nlm.nih.gov/pubmed/20429872 http://dx.doi.org/10.1186/1471-2350-11-66

Ejemplares similares

ApoA5 lowers triglyceride levels via suppression of ANGPTL3/8-mediated LPL inhibition
por: Chen, Yan Q., et al.
Publicado: (2021)

Incidence of Diabetes in the Working Population in Spain: Results from the ICARIA Cohort
por: Vazquez, Luis Alberto, et al.
Publicado: (2018)

Amelioration of Hypertriglyceridemia with Hypo-Alpha-Cholesterolemia in LPL Deficient Mice by Hematopoietic Cell-Derived LPL
por: Ding, Yinyuan, et al.
Publicado: (2011)

Autophagy Alteration in ApoA-I Related Systemic Amyloidosis
por: Del Giudice, Rita, et al.
Publicado: (2022)

Alterations in sorting and secretion of hepatic apoA5 induce hypertriglyceridemia due to short-term use of olanzapine
por: Huang, Piao-Piao, et al.
Publicado: (2022)

HDL/ApoA-1 infusion and ApoA-1 gene therapy in atherosclerosis
por: Chyu, Kuang-Yuh, et al.
Publicado: (2015)

Serum Levels of ApoA1 and ApoA2 Are Associated with Cognitive Status in Older Men
por: Ma, Cheng, et al.
Publicado: (2015)

Different Functional and Structural Characteristics between ApoA-I and ApoA-4 in Lipid-Free and Reconstituted HDL State: ApoA-4 Showed Less Anti-Atherogenic Activity
por: Yoo, Jeong-Ah, et al.
Publicado: (2015)

SIDT2 Associates with Apolipoprotein A1 (ApoA1) and Facilitates ApoA1 Secretion in Hepatocytes
por: Sampieri, Alicia, et al.
Publicado: (2023)

Familial chylomicronemia syndrome in children: a diagnosis challenge
por: Ariza, María José, et al.
Publicado: (2022)

Omega 3 fatty acids induce a marked reduction of apolipoprotein B48 when added to fluvastatin in patients with type 2 diabetes and mixed hyperlipidemia: a preliminary report
por: Valdivielso, Pedro, et al.
Publicado: (2009)

Apolipoprotein E content of VLDL limits LPL-mediated triglyceride hydrolysis
por: Whitacre, Brynne E., et al.
Publicado: (2021)

ApoA-1 in Diabetes: Damaged Goods
por: Ory, Daniel S., et al.
Publicado: (2010)

Gene transfer of wild-type apoA-I and apoA-I Milano reduce atherosclerosis to a similar extent
por: Lebherz, Corinna, et al.
Publicado: (2007)

ApoA-I mimetic administration, but not increased apoA-I-containing HDL, inhibits tumour growth in a mouse model of inherited breast cancer
por: Cedó, Lídia, et al.
Publicado: (2016)

Lipoprotein lipase activity and mass, apolipoprotein C-II mass and polymorphisms of apolipoproteins E and A5 in subjects with prior acute hypertriglyceridaemic pancreatitis
por: Coca-Prieto, Inmaculada, et al.
Publicado: (2009)

Brain ApoA-I, ApoJ and ApoE Immunodetection in Cerebral Amyloid Angiopathy
por: Camacho, Jessica, et al.
Publicado: (2019)

LPL gene Pvu II polymorphism and hypertriglyceridemia: a meta-analysis involving 1,640 subjects
por: Li, Yan-yan, et al.
Publicado: (2017)

The unsolved mystery of apoA-I recycling in adipocyte
por: Wang, Shuai, et al.
Publicado: (2016)

ApoC-III ASO promotes tissue LPL activity in the absence of apoE-mediated TRL clearance
por: Ramms, Bastian, et al.
Publicado: (2019)

A Clinical Case of a Homozygous Deletion in the APOA5 Gene with Severe Hypertriglyceridemia
por: Vasiluev, Petr Andreevich, et al.
Publicado: (2022)

LCAT, ApoD, and ApoA1 Expression and Review of Cholesterol Deposition in the Cornea
por: Flores, Rhonda, et al.
Publicado: (2019)

Long-term risk of a major cardiovascular event by apoB, apoA-1, and the apoB/apoA-1 ratio—Experience from the Swedish AMORIS cohort: A cohort study
por: Walldius, Göran, et al.
Publicado: (2021)

A Specific Tubular ApoA-I Distribution Is Associated to FSGS Recurrence after Kidney Transplantation
por: Jacobs-Cachá, Conxita, et al.
Publicado: (2021)

APOE, CETP and LPL genes show strong association with lipid levels in Greek children()
por: Smart, M.C., et al.
Publicado: (2010)

Effects of Individual Amino Acids on PPARα Transactivation, mTORC1 Activation, ApoA-I Transcription and pro-ApoA-I Secretion
por: Tayyeb, Jehad Z., et al.
Publicado: (2022)

Comparison of the structure-function properties of wild-type human apoA-V and a C-terminal truncation associated with elevated plasma triglycerides
por: Stankov, Sylvia, et al.
Publicado: (2023)

Hypertriglyceridemia in Apoa5(–/–) mice results from reduced amounts of lipoprotein lipase in the capillary lumen
por: Yang, Ye, et al.
Publicado: (2023)

Effect of apoA-I on cholesterol release and apoE secretion in human mature adipocytes
por: Bencharif, Karima, et al.
Publicado: (2010)

Identification of a novel LPL nonsense variant and further insights into the complex etiology and expression of hypertriglyceridemia-induced acute pancreatitis
por: Li, Xiao-Yao, et al.
Publicado: (2020)

APOA5 Q97X Mutation Identified through homozygosity mapping causes severe hypertriglyceridemia in a Chilean consanguineous family
por: Dussaillant, Catalina, et al.
Publicado: (2012)

Influences of APOA5 Variants on Plasma Triglyceride Levels in Uyghur Population
por: Li, Shuyuan, et al.
Publicado: (2014)

Estrogen lowers triglyceride via regulating hepatic APOA5 expression
por: Luo, Fei, et al.
Publicado: (2017)

The Effects of Parenteral K1 Administration in Pseudoxanthoma Elasticum Patients Versus Controls. A Pilot Study
por: Carrillo-Linares, Juan Luis, et al.
Publicado: (2018)

Human apoA-I[Lys107del] mutation affects lipid surface behavior of apoA-I and its ability to form large nascent HDL
por: Gorshkova, Irina N., et al.
Publicado: (2022)

Subclinical atherosclerosis burden in non-diabetic hypertensives treated in primary care center: the IMTABI study
por: Ramírez-Torres, José M., et al.
Publicado: (2023)

HDL-apoA-I Exchange: Rapid Detection and Association with Atherosclerosis
por: Borja, Mark S., et al.
Publicado: (2013)

Apolipoprotein A-I (ApoA-I), Immunity, Inflammation and Cancer
por: Georgila, Konstantina, et al.
Publicado: (2019)

Clinical ApoA‐IV amyloid is associated with fibrillogenic signal sequence
por: Canetti, Diana, et al.
Publicado: (2021)

ApoB/apoA1 is an effective predictor of coronary heart disease risk in overweight and obesity()
por: Lu, Min, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_ljtj0im676c07riehg4vn6uo3f