Molecular Targeting of Carbonic Anhydrase IX in Mice with Hypoxic HT29 Colorectal Tumor Xenografts

BACKGROUND: Carbonic anhydrase IX (CAIX) is a membrane spanning protein involved in the enzymatic regulation of tumor acid-base balance. CAIX has been shown to be elevated in a number of hypoxic tumor types. The purpose of this study was to determine the efficiency of intact and IgG fragments of cG2...

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Detalles Bibliográficos
Autores principales: Carlin, Sean, Khan, Nahida, Ku, Thomas, Longo, Valerie A., Larson, Steve M., Smith-Jones, Peter M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877709/
https://www.ncbi.nlm.nih.gov/pubmed/20523727
http://dx.doi.org/10.1371/journal.pone.0010857

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