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Effect of Neuraminidase Inhibitor–Resistant Mutations on Pathogenicity of Clade 2.2 A/Turkey/15/06 (H5N1) Influenza Virus in Ferrets
The acquisition of neuraminidase (NA) inhibitor resistance by H5N1 influenza viruses has serious clinical implications, as this class of drugs can be an essential component of pandemic control measures. The continuous evolution of the highly pathogenic H5N1 influenza viruses results in the emergence...
Autores principales: | Ilyushina, Natalia A., Seiler, Jon P., Rehg, Jerold E., Webster, Robert G., Govorkova, Elena A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877746/ https://www.ncbi.nlm.nih.gov/pubmed/20523902 http://dx.doi.org/10.1371/journal.ppat.1000933 |
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