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Notch and Wnt Signaling, Physiological Stimuli and Postnatal Myogenesis

Adult skeletal muscle stem cells, termed satellite cells are imperative to muscle regeneration. Much work has been performed on satellite cell identification and the subsequent activation of the myogenic response but the regulation of satellite cells including its activation is not well elucidated....

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Detalles Bibliográficos
Autor principal: Tsivitse, Susan
Formato: Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878172/
https://www.ncbi.nlm.nih.gov/pubmed/20567496
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author Tsivitse, Susan
author_facet Tsivitse, Susan
author_sort Tsivitse, Susan
collection PubMed
description Adult skeletal muscle stem cells, termed satellite cells are imperative to muscle regeneration. Much work has been performed on satellite cell identification and the subsequent activation of the myogenic response but the regulation of satellite cells including its activation is not well elucidated. The purpose of this review article is to synthesize what the literature reveals in regards to the current understanding of satellite cells including their contribution to muscle repair and growth following physiological stimuli. In addition, this review article will describe the recent findings on the roles of the classic developmental signaling pathways, Notch and Wnt, to the myogenic response in various muscle injury models. This purpose of this summary is to bring awareness of the impact that muscle contraction models have on the local and systemic environment of adult muscle stem cells which will be beneficial for comprehending and treatment development for muscle -associated ailments and other organ diseases.
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spelling pubmed-28781722010-06-21 Notch and Wnt Signaling, Physiological Stimuli and Postnatal Myogenesis Tsivitse, Susan Int J Biol Sci Review Adult skeletal muscle stem cells, termed satellite cells are imperative to muscle regeneration. Much work has been performed on satellite cell identification and the subsequent activation of the myogenic response but the regulation of satellite cells including its activation is not well elucidated. The purpose of this review article is to synthesize what the literature reveals in regards to the current understanding of satellite cells including their contribution to muscle repair and growth following physiological stimuli. In addition, this review article will describe the recent findings on the roles of the classic developmental signaling pathways, Notch and Wnt, to the myogenic response in various muscle injury models. This purpose of this summary is to bring awareness of the impact that muscle contraction models have on the local and systemic environment of adult muscle stem cells which will be beneficial for comprehending and treatment development for muscle -associated ailments and other organ diseases. Ivyspring International Publisher 2010-05-15 /pmc/articles/PMC2878172/ /pubmed/20567496 Text en © Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.
spellingShingle Review
Tsivitse, Susan
Notch and Wnt Signaling, Physiological Stimuli and Postnatal Myogenesis
title Notch and Wnt Signaling, Physiological Stimuli and Postnatal Myogenesis
title_full Notch and Wnt Signaling, Physiological Stimuli and Postnatal Myogenesis
title_fullStr Notch and Wnt Signaling, Physiological Stimuli and Postnatal Myogenesis
title_full_unstemmed Notch and Wnt Signaling, Physiological Stimuli and Postnatal Myogenesis
title_short Notch and Wnt Signaling, Physiological Stimuli and Postnatal Myogenesis
title_sort notch and wnt signaling, physiological stimuli and postnatal myogenesis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878172/
https://www.ncbi.nlm.nih.gov/pubmed/20567496
work_keys_str_mv AT tsivitsesusan notchandwntsignalingphysiologicalstimuliandpostnatalmyogenesis