Cargando…

NMR Method for Measuring Carbon-13 Isotopic Enrichment of Metabolites in Complex Solutions

Isotope-based methods are commonly used for metabolic flux analysis and metabolite quantification in biological extracts. Nuclear magnetic resonance (NMR) spectroscopy is a powerful analytical tool for these studies because NMR can unambiguously identify compounds and accurately measure (13)C enrich...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lewis, Ian A., Karsten, Ryan H., Norton, Mark E., Tonelli, Marco, Westler, William M., Markley, John L.
Formato:	Texto
Lenguaje:	English
Publicado:	American Chemical Society 2010
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878175/ https://www.ncbi.nlm.nih.gov/pubmed/20459129 http://dx.doi.org/10.1021/ac100565b

Ejemplares similares

rNMR: open source software for identifying and quantifying metabolites in NMR spectra
por: Lewis, Ian A, et al.
Publicado: (2009)

Simultaneous Quantification and Identification of Individual Chemicals in Metabolite Mixtures by Two-Dimensional Extrapolated Time-Zero (1)H−(13)C HSQC (HSQC(0))
por: Hu, Kaifeng, et al.
Publicado: (2011)

Integrative NMR for biomolecular research
por: Lee, Woonghee, et al.
Publicado: (2016)

Correction to Simultaneous Quantification and Identification of Individual Chemicals in Metabolite Mixtures by Two-Dimensional Extrapolated Time-Zero (1)H–(13)C HSQC (HSQC(0))
por: Hu, Kaifeng, et al.
Publicado: (2012)

Hyperfine-Shifted (13)C and (15)N NMR Signals from Clostridium pasteurianum Rubredoxin: Extensive Assignments and Quantum Chemical Verification
por: Lin, I-Jin, et al.
Publicado: (2009)

NMR Investigations of the Rieske Protein from Thermus thermophilus Support a Coupled Proton and Electron Transfer Mechanism
por: Hsueh, Kuang-Lung, et al.
Publicado: (2010)

Partial (13)C isotopic enrichment of nucleoside monophosphates: useful reporters for NMR structural studies
por: Kishore, Anita I., et al.
Publicado: (2005)

Solution Structural Studies of GTP:Adenosylcobinamide-Phosphateguanylyl Transferase (CobY) from Methanocaldococcus jannaschii
por: Singarapu, Kiran K., et al.
Publicado: (2015)

POKY software tools encapsulating assignment strategies for solution and solid-state protein NMR data
por: Manthey, Ira, et al.
Publicado: (2022)

PINE-SPARKY: graphical interface for evaluating automated probabilistic peak assignments in protein NMR spectroscopy
por: Lee, Woonghee, et al.
Publicado: (2009)

Structural Characterization of Hsp12, the Heat Shock Protein from Saccharomyces cerevisiae, in Aqueous Solution Where It Is Intrinsically Disordered and in Detergent Micelles Where It Is Locally α-Helical
por: Singarapu, Kiran K., et al.
Publicado: (2011)

NMRFAM-SPARKY: enhanced software for biomolecular NMR spectroscopy
por: Lee, Woonghee, et al.
Publicado: (2015)

The Complex Energy Landscape of the Protein IscU
por: Bothe, Jameson R., et al.
Publicado: (2015)

NMR-Based Identification of Metabolites in Polar and Non-Polar Extracts of Avian Liver
por: Fathi, Fariba, et al.
Publicado: (2017)

NMRmix: A Tool for the Optimization of Compound Mixtures in 1D (1)H NMR Ligand Affinity Screens
por: Stark, Jaime L., et al.
Publicado: (2016)

NMRbot: Python scripts enable high-throughput data collection on current Bruker BioSpin NMR spectrometers
por: Clos, Lawrence J., et al.
Publicado: (2013)

Carbon-13 NMR of flavonoids
por: Agrawal, Pradeep K.
Publicado: (1989)

Tracking Stable Isotope Enrichment in Tree Seedlings with Solid-State NMR Spectroscopy
por: Norris, Charlotte E., et al.
Publicado: (2012)

Robust, Integrated Computational Control of NMR Experiments to Achieve Optimal Assignment by ADAPT-NMR
por: Bahrami, Arash, et al.
Publicado: (2012)

Accurate Structure and Dynamics of the Metal-Site of Paramagnetic Metalloproteins from NMR Parameters Using Natural Bond Orbitals
por: Hansen, D. Flemming, et al.
Publicado: (2012)

Probing Protein-Protein Interactions Using Asymmetric Labeling and Carbonyl-Carbon Selective Heteronuclear NMR Spectroscopy
por: Larsen, Erik K., et al.
Publicado: (2018)

(1)H-NMR and (13)C-NMR dataset for some oxidative metabolites of CRA13 and their analogs
por: Hassan, Ahmed H.E., et al.
Publicado: (2018)

Stable carbon and nitrogen isotope enrichment in primate tissues
por: Crowley, Brooke E., et al.
Publicado: (2010)

Hyperfine-Shifted (13)C Resonance Assignments in an Iron−Sulfur Protein with Quantum Chemical Verification: Aliphatic C−H···S 3-Center−4-Electron Interactions
por: Westler, William M., et al.
Publicado: (2011)

Quantification of Stable Isotope Traces Close to Natural Enrichment in Human Plasma Metabolites Using Gas Chromatography-Mass Spectrometry
por: Krämer, Lisa, et al.
Publicado: (2018)

Positional Enrichment by Proton Analysis (PEPA): A One‐Dimensional (1)H‐NMR Approach for (13)C Stable Isotope Tracer Studies in Metabolomics
por: Vinaixa, Maria, et al.
Publicado: (2017)

Application of (13)C Quantitative NMR Spectroscopy to Isotopic Analyses for Vanillin Authentication Source †
por: Pironti, Concetta, et al.
Publicado: (2021)

Carbon-13 NMR spectroscopy : high-resolution methods and applications in organic chemistry and biochemistry /
por: Breitmaier, Eberhard, 1939-
Publicado: (1987)

Mammalian production of an isotopically enriched outer domain of the HIV-1 gp120 glycoprotein for NMR spectroscopy
por: Sastry, Mallika, et al.
Publicado: (2011)

Two-dimensional concurrent HMQC-COSY as an approach for small molecule chemical shift assignment and compound identification
por: Hu, Kaifeng, et al.
Publicado: (2011)

Intramolecular carbon isotope signals reflect metabolite allocation in plants
por: Wieloch, Thomas, et al.
Publicado: (2022)

Multidimensional High-Resolution Magic Angle Spinning and Solution-State NMR Characterization of (13)C-labeled Plant Metabolites and Lignocellulose
por: Mori, Tetsuya, et al.
Publicado: (2015)

Trophic Enrichment Factors of Carbon and Nitrogen Isotopic Ratios (Δ(13)C and Δ(15)N) in Four Marine Ciliates
por: Park, Jun Young, et al.
Publicado: (2021)

Stable-Isotope-Aided NMR Spectroscopy
por: Miyanoiri, Yohei, et al.
Publicado: (2018)

Solid-state NMR of unlabeled plant cell walls: high-resolution structural analysis without isotopic enrichment
por: Zhao, Wancheng, et al.
Publicado: (2021)

Deuterium Isotope Effects on (13)C-NMR Chemical Shifts of 10-Hydroxybenzo[h]quinolines
por: Hansen, Poul Erik, et al.
Publicado: (2013)

Selective isotope labeling for NMR structure determination of proteins in complex with unlabeled ligands
por: Tripsianes, Konstantinos, et al.
Publicado: (2019)

ADAPT-NMR Enhancer: complete package for reduced dimensionality in protein NMR spectroscopy
por: Lee, Woonghee, et al.
Publicado: (2013)

Electromagnetic isotope separators and applications of electromagnetically enriched isotopes
por: Koch, J, et al.
Publicado: (1958)

MIDcor, an R-program for deciphering mass interferences in mass spectra of metabolites enriched in stable isotopes
por: Selivanov, Vitaly A., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_fvglk1pfr7061p9chj5valqqtr