Zinc Cream and Reliability of Tuberculosis Skin Testing

In 50 healthy Peruvian shantytown residents, zinc cream applied to tuberculosis skin-test sitescaused a 32% increase in induration compared with placebo cream. Persons with lower plasma zinc had smaller skin-test reactions and greater augmentation with zinc cream. Zinc deficiency caused false-negati...

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Detalles Bibliográficos
Autores principales: Rao, V. Bhargavi, Pelly, Tom F., Gilman, Robert H., Cabrera, Lilia, Delgado, Jose, Soto, Giselle, Friedland, Jon S., Escombe, A. Roderick, Black, Robert E., Evans, Carlton A.
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2007
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878245/
https://www.ncbi.nlm.nih.gov/pubmed/18214192
http://dx.doi.org/10.3201/eid1307.070227
Descripción
Sumario:In 50 healthy Peruvian shantytown residents, zinc cream applied to tuberculosis skin-test sitescaused a 32% increase in induration compared with placebo cream. Persons with lower plasma zinc had smaller skin-test reactions and greater augmentation with zinc cream. Zinc deficiency caused false-negative skin-test results, and topical zinc supplementation augmented antimycobacterial immune responses enough to improve diagnosis.

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