Zinc Cream and Reliability of Tuberculosis Skin Testing

In 50 healthy Peruvian shantytown residents, zinc cream applied to tuberculosis skin-test sitescaused a 32% increase in induration compared with placebo cream. Persons with lower plasma zinc had smaller skin-test reactions and greater augmentation with zinc cream. Zinc deficiency caused false-negati...

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Autores principales: Rao, V. Bhargavi, Pelly, Tom F., Gilman, Robert H., Cabrera, Lilia, Delgado, Jose, Soto, Giselle, Friedland, Jon S., Escombe, A. Roderick, Black, Robert E., Evans, Carlton A.
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2007
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878245/
https://www.ncbi.nlm.nih.gov/pubmed/18214192
http://dx.doi.org/10.3201/eid1307.070227
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author Rao, V. Bhargavi
Pelly, Tom F.
Gilman, Robert H.
Cabrera, Lilia
Delgado, Jose
Soto, Giselle
Friedland, Jon S.
Escombe, A. Roderick
Black, Robert E.
Evans, Carlton A.
author_facet Rao, V. Bhargavi
Pelly, Tom F.
Gilman, Robert H.
Cabrera, Lilia
Delgado, Jose
Soto, Giselle
Friedland, Jon S.
Escombe, A. Roderick
Black, Robert E.
Evans, Carlton A.
author_sort Rao, V. Bhargavi
collection PubMed
description In 50 healthy Peruvian shantytown residents, zinc cream applied to tuberculosis skin-test sitescaused a 32% increase in induration compared with placebo cream. Persons with lower plasma zinc had smaller skin-test reactions and greater augmentation with zinc cream. Zinc deficiency caused false-negative skin-test results, and topical zinc supplementation augmented antimycobacterial immune responses enough to improve diagnosis.
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spelling pubmed-28782452010-06-03 Zinc Cream and Reliability of Tuberculosis Skin Testing Rao, V. Bhargavi Pelly, Tom F. Gilman, Robert H. Cabrera, Lilia Delgado, Jose Soto, Giselle Friedland, Jon S. Escombe, A. Roderick Black, Robert E. Evans, Carlton A. Emerg Infect Dis Dispatch In 50 healthy Peruvian shantytown residents, zinc cream applied to tuberculosis skin-test sitescaused a 32% increase in induration compared with placebo cream. Persons with lower plasma zinc had smaller skin-test reactions and greater augmentation with zinc cream. Zinc deficiency caused false-negative skin-test results, and topical zinc supplementation augmented antimycobacterial immune responses enough to improve diagnosis. Centers for Disease Control and Prevention 2007-07 /pmc/articles/PMC2878245/ /pubmed/18214192 http://dx.doi.org/10.3201/eid1307.070227 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Rao, V. Bhargavi
Pelly, Tom F.
Gilman, Robert H.
Cabrera, Lilia
Delgado, Jose
Soto, Giselle
Friedland, Jon S.
Escombe, A. Roderick
Black, Robert E.
Evans, Carlton A.
Zinc Cream and Reliability of Tuberculosis Skin Testing
title Zinc Cream and Reliability of Tuberculosis Skin Testing
title_full Zinc Cream and Reliability of Tuberculosis Skin Testing
title_fullStr Zinc Cream and Reliability of Tuberculosis Skin Testing
title_full_unstemmed Zinc Cream and Reliability of Tuberculosis Skin Testing
title_short Zinc Cream and Reliability of Tuberculosis Skin Testing
title_sort zinc cream and reliability of tuberculosis skin testing
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878245/
https://www.ncbi.nlm.nih.gov/pubmed/18214192
http://dx.doi.org/10.3201/eid1307.070227
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