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Immune function and health outcomes in women with depression

This research reports immune function and health outcomes in women with depression, as compared with a non-depressed control group. Using Psychoneuroimmunolgy theory and a descriptive comparison design, scores on the Beck Depression Inventory (BDI) were used to divide 40 non-hospitalized Caucasian w...

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Detalles Bibliográficos
Autores principales: Howk, Cherie, Bennett, Mary
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878291/
https://www.ncbi.nlm.nih.gov/pubmed/20438639
http://dx.doi.org/10.1186/1751-0759-4-3
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author Howk, Cherie
Bennett, Mary
author_facet Howk, Cherie
Bennett, Mary
author_sort Howk, Cherie
collection PubMed
description This research reports immune function and health outcomes in women with depression, as compared with a non-depressed control group. Using Psychoneuroimmunolgy theory and a descriptive comparison design, scores on the Beck Depression Inventory (BDI) were used to divide 40 non-hospitalized Caucasian women between the ages of 18 and 65 years into either the control or depression comparison group. Women with depression were found to report significantly more incidences of illness over the previous two months and they were found to have significantly more indicators of illness at the time of the exam as compared to the controls. However, contrary to what has been documented in some earlier studies of depression, women with depression were not found to have significantly different immune function measures as compared to the control group. There was also no significant correlation between scores on the BDI and natural killer cell cytotoxicity in this study. While these findings support a connection between depression and both increased self-report of illness and increased signs and symptoms of minor illness or inflammation on physical exam, this study was not able to document that these effects were related to decreased immune function, as measured by natural killer cell activity or white blood cell counts.
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spelling pubmed-28782912010-05-29 Immune function and health outcomes in women with depression Howk, Cherie Bennett, Mary Biopsychosoc Med Research This research reports immune function and health outcomes in women with depression, as compared with a non-depressed control group. Using Psychoneuroimmunolgy theory and a descriptive comparison design, scores on the Beck Depression Inventory (BDI) were used to divide 40 non-hospitalized Caucasian women between the ages of 18 and 65 years into either the control or depression comparison group. Women with depression were found to report significantly more incidences of illness over the previous two months and they were found to have significantly more indicators of illness at the time of the exam as compared to the controls. However, contrary to what has been documented in some earlier studies of depression, women with depression were not found to have significantly different immune function measures as compared to the control group. There was also no significant correlation between scores on the BDI and natural killer cell cytotoxicity in this study. While these findings support a connection between depression and both increased self-report of illness and increased signs and symptoms of minor illness or inflammation on physical exam, this study was not able to document that these effects were related to decreased immune function, as measured by natural killer cell activity or white blood cell counts. BioMed Central 2010-05-03 /pmc/articles/PMC2878291/ /pubmed/20438639 http://dx.doi.org/10.1186/1751-0759-4-3 Text en Copyright ©2010 Howk and Bennett; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Howk, Cherie
Bennett, Mary
Immune function and health outcomes in women with depression
title Immune function and health outcomes in women with depression
title_full Immune function and health outcomes in women with depression
title_fullStr Immune function and health outcomes in women with depression
title_full_unstemmed Immune function and health outcomes in women with depression
title_short Immune function and health outcomes in women with depression
title_sort immune function and health outcomes in women with depression
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878291/
https://www.ncbi.nlm.nih.gov/pubmed/20438639
http://dx.doi.org/10.1186/1751-0759-4-3
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