Exon Exchange Approach to Repair Duchenne Dystrophin Transcripts

BACKGROUND: Trans-splicing strategies for mRNA repair involve engineered transcripts designed to anneal target mRNAs in order to interfere with their natural splicing, giving rise to mRNA chimeras where endogenous mutated exons have been replaced by exogenous replacement sequences. A number of trans...

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Detalles Bibliográficos
Autores principales: Lorain, Stéphanie, Peccate, Cécile, Le Hir, Maëva, Garcia, Luis
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878348/
https://www.ncbi.nlm.nih.gov/pubmed/20531943
http://dx.doi.org/10.1371/journal.pone.0010894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878348/
https://www.ncbi.nlm.nih.gov/pubmed/20531943
http://dx.doi.org/10.1371/journal.pone.0010894

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