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P2X1 receptor mobility and trafficking; regulation by receptor insertion and activation

P2X1 receptors for ATP contribute to signalling in a variety of cell types and following stimulation undergo rapid desensitisation (within 1 s), and require ∼5 min to recover. In HEK293 cells P2X1 receptors C-terminally tagged with enhanced green fluorescent protein (P2X1-eGFP) were predominantly ex...

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Detalles Bibliográficos
Autores principales: Lalo, Ulyana, Allsopp, Rebecca C, Mahaut-Smith, Martyn P, Evans, Richard J
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878604/
https://www.ncbi.nlm.nih.gov/pubmed/20374431
http://dx.doi.org/10.1111/j.1471-4159.2010.06730.x