Human Lipoxygenase Pathway Gene Variation and Association with Markers of Subclinical Atherosclerosis in the Diabetes Heart Study

Aims. Genes of the 5-lipoxygenase pathway are compelling candidates for atherosclerosis. We hypothesize that polymorphisms in ALOX12, ALOX15, ALOX5, and ALOX5AP genes are associated with subclinical atherosclerosis in multiple vascular beds. Methods. Families with two or more siblings with type 2 di...

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Detalles Bibliográficos
Autores principales: Burdon, Kathryn P., Rudock, Megan E., Lehtinen, Allison B., Langefeld, Carl D., Bowden, Donald W., Register, Thomas C., Liu, Yongmei, Freedman, Barry I., Carr, J. Jeffrey, Hedrick, Catherine C., Rich, Stephen S.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878676/
https://www.ncbi.nlm.nih.gov/pubmed/20592751
http://dx.doi.org/10.1155/2010/170153

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