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Whole lung lavage for pulmonary alveolar proteinosis

A 26-year-old male presented with complaints of dry cough of six months and progressive breathlessness of three months duration. He was coughing out milky white sputum for two months and had lost 12 kg weight in two months. He had an evening rise in temperature of one month duration. Clinically, the...

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Autores principales: Jayaraman, S., Gayathri, A. R., Senthil Kumar, P., Santosham, Rajeev, Santosham, Rajan, Narasimhan, R
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878711/
https://www.ncbi.nlm.nih.gov/pubmed/20539770
http://dx.doi.org/10.4103/0970-2113.59267
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author Jayaraman, S.
Gayathri, A. R.
Senthil Kumar, P.
Santosham, Rajeev
Santosham, Rajan
Narasimhan, R
author_facet Jayaraman, S.
Gayathri, A. R.
Senthil Kumar, P.
Santosham, Rajeev
Santosham, Rajan
Narasimhan, R
author_sort Jayaraman, S.
collection PubMed
description A 26-year-old male presented with complaints of dry cough of six months and progressive breathlessness of three months duration. He was coughing out milky white sputum for two months and had lost 12 kg weight in two months. He had an evening rise in temperature of one month duration. Clinically, the patient was in respiratory distress and the respiratory system examination revealed bilateral velcro crackles. High resolution computed tomography chest showed bilateral diffuse reticulonodular opacities and “Crazy Paving” pattern suggestive of alveolar proteinosis. Broncho alveolar lavage showed eosinophilic granular material, which was periodic acid-Schiff positive. Open lung biopsy was done to confirm the diagnosis and the histopathologic examination revealed eosinophilic secretions with granular appearance suggestive of pulmonary alveolar proteinosis. Subsequently, patient underwent bilateral sequential whole lung lavage under general anesthesia. Patient showed marked clinical and radiological improvement after sequential whole lung lavage.
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spelling pubmed-28787112010-06-10 Whole lung lavage for pulmonary alveolar proteinosis Jayaraman, S. Gayathri, A. R. Senthil Kumar, P. Santosham, Rajeev Santosham, Rajan Narasimhan, R Lung India Case Report A 26-year-old male presented with complaints of dry cough of six months and progressive breathlessness of three months duration. He was coughing out milky white sputum for two months and had lost 12 kg weight in two months. He had an evening rise in temperature of one month duration. Clinically, the patient was in respiratory distress and the respiratory system examination revealed bilateral velcro crackles. High resolution computed tomography chest showed bilateral diffuse reticulonodular opacities and “Crazy Paving” pattern suggestive of alveolar proteinosis. Broncho alveolar lavage showed eosinophilic granular material, which was periodic acid-Schiff positive. Open lung biopsy was done to confirm the diagnosis and the histopathologic examination revealed eosinophilic secretions with granular appearance suggestive of pulmonary alveolar proteinosis. Subsequently, patient underwent bilateral sequential whole lung lavage under general anesthesia. Patient showed marked clinical and radiological improvement after sequential whole lung lavage. Medknow Publications 2010 /pmc/articles/PMC2878711/ /pubmed/20539770 http://dx.doi.org/10.4103/0970-2113.59267 Text en © Lung India http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Jayaraman, S.
Gayathri, A. R.
Senthil Kumar, P.
Santosham, Rajeev
Santosham, Rajan
Narasimhan, R
Whole lung lavage for pulmonary alveolar proteinosis
title Whole lung lavage for pulmonary alveolar proteinosis
title_full Whole lung lavage for pulmonary alveolar proteinosis
title_fullStr Whole lung lavage for pulmonary alveolar proteinosis
title_full_unstemmed Whole lung lavage for pulmonary alveolar proteinosis
title_short Whole lung lavage for pulmonary alveolar proteinosis
title_sort whole lung lavage for pulmonary alveolar proteinosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878711/
https://www.ncbi.nlm.nih.gov/pubmed/20539770
http://dx.doi.org/10.4103/0970-2113.59267
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